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Peer-reviewed veterinary case report

Nasal and sinus tumors in dogs, cats, and horses from 1964-73

By Madewell Br et al.·Published in American Journal of Veterinary Research·1976·View original on Semantic Scholar

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Original publication title: Neoplasms of the nasal passages and paranasal sinuses in domesticated animals as reported by 13 veterinary colleges.

Species:
dog

Plain-English summary

A group of dogs with nasal tumors showed symptoms like nasal and eye discharge, facial deformities, and noisy breathing. Most of these tumors were found to be malignant, and the dogs had often been experiencing symptoms for about three months before being diagnosed. Treatment options included surgery and radiation therapy, but the average survival time after treatment was around 6.7 months. Unfortunately, the prognosis for these dogs was generally poor due to the aggressive nature of the tumors.

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Abstract

Three hundred cases of primary neoplasms involving the nasal cavity or paranasal sinuses were found among the reports of 12,300 microscopically confirmed neoplasms. The multispecies data were compiled from abstracts of medical records by 13 colleges of veterinary medicine in the United States and Canada from 1964 to 1973. Significant numbers of neoplasms were observed in dogs, horses, and cats. Intranasal neoplasms were more frequent than those of the paranasal sinuses in dogs and cats. Only cats had a sex difference in the occurrence of nasal neoplasms, with a male predilection. The frequency of neoplasms of the nasal cavity and paranasal sinuses increased with age in all species examined. A clear relationship could not be established between nose length and of intranasal neoplasms. Of the tumors, 80% were malignant in dogs, 68% in horses, and 91% in cats. Detailed review of medical records in a subset of 49 dogs with neoplasms of the nasal passage and paranasal sinuses revealed major clinical signs of nasal and ocular discharge, facial deformity, and stertorous breathing. Median duration of signs prior to diagnosis was 3 months and 95% of the dogs had been given treatment prior to definitive diagnosis. All 49 tumors were malignant; 27 were classified histologically as carcinomas and 22 were sarcomas. Nineteen dogs were treated, using surgery alone or in combination with radiation therapy. Median survival duration was 5 months (mean 6.7 mo).

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Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/937809