Peer-reviewed veterinary case report
Nephrotic syndrome in Dobermann linked to sulfadimethoxine treatment
By Vasilopulos, R J et al.Ā·Published in The Journal of small animal practiceĀ·2005Ā·Department of Clinical Sciences, United StatesĀ·View original on PubMed ā
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Original publication title: Nephrotic syndrome associated with administration of sulfadimethoxine/ormetoprim in a dobermann.
- Species:
- dog
Plain-English summary
A young Doberman was diagnosed with nephrotic syndrome, a serious condition where the kidneys leak protein, after being given a sulfonamide antibiotic called sulfadimethoxine/ormetoprim. The dog showed signs of illness, but thankfully, the symptoms improved quickly after stopping the medication and providing supportive care. This case highlights the importance of checking a pet's medication history when they have kidney problems, as certain drugs can cause serious side effects.
People also search for: Doberman kidney disease symptoms Ā· nephrotic syndrome in dogs Ā· sulfonamide side effects in dogs
Abstract
This case report describes sulphonamide-induced nephrotic syndrome in a young dobermann dog. The clinical signs and laboratory abnormalities resolved shortly after discontinuation of the sulphonamide antibiotic and with generalised supportive care. Since nephrotic syndrome typically carries a guarded prognosis in veterinary medicine and is poorly responsive to therapy, a thorough drug history should be an important part of the investigation of any animal with a protein-losing nephropathy.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15909446/