Peer-reviewed veterinary case report
Nephrotic syndrome (NS) and pregnancy in rat--evaluation of kidney in electron microscopy.
- Journal:
- Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina
- Year:
- 2004
- Authors:
- Pedrycz, Agnieszka et al.
- Affiliation:
- Department of Histology and Embryology
- Species:
- rodent
Abstract
The purpose of this study was the histological evaluation of kidneys on the ultrastructural level. In the experiment there were used pregnant female rats in which gestation coexisted with adriamycin-induced NS. Results showed numerous focal changes in kidney glomerules and tubules which were the evidence of increased protein loss and filtration barrier damage as the main cause of increased permeability for proteins.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16145984/