Peer-reviewed veterinary case report
Neuregulin-1 alleviates Charcot-Marie-Tooth disease in rats.
- Journal:
- Nature medicine
- Year:
- 2014
- Authors:
- Martini, Rudolf
- Affiliation:
- Department of Neurology · Germany
- Species:
- rodent
Abstract
Disrupted differentiation of Schwann cells contributes to axonal loss in a rat model of Charcot-Marie-Tooth 1A neuropathy. Early neuregulin-1 treatment promotes Schwann cell differentiation, preserves axons and restores nerve function in this model.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25198045/