Peer-reviewed veterinary case report
Neuroendocrine anal sac gland cancer in an 8-year-old dog
By Ogawa, Bunichiro et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2011·Tokyo University of Agriculture and Technology, Japan·View original on PubMed →
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Original publication title: Neuroendocrine carcinoma of the apocrine glands of the anal sac in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old male mixed Labrador Retriever was found to have a tumor near the anal sac, which was causing concern. After testing, the tumor was identified as a neuroendocrine carcinoma, a type of cancer that originates from the glands in that area. Treatment options for this type of cancer can vary, but it's important for pet owners to discuss potential therapies with their veterinarian to determine the best course of action. Early detection and intervention can be crucial for managing this condition.
People also search for: dog anal sac tumor · Labrador Retriever cancer treatment · what to do about dog anal sac growth
Abstract
A perianal subcutaneous tumor involving the anal sac developed in an 8-year-old male mixed Labrador Retriever dog. Histologically, this tumor showed typical features of the solid-type carcinoma of the apocrine glands of the anal sac. However, neoplastic cells were immunoreactive for cytokeratin 8, chromogranin A, vasoactive intestinal peptide, neuron-specific enolase, and synaptophysin, and negative for S-100 protein, α-smooth muscle actin, vimentin, glucagon, insulin, somatostatin, carcinoembryonic antigen, serotonin, and parathyroid hormone-related protein. Considering the distribution of chromogranin A-positive cells within the anal sac apocrine glands, this tumor was diagnosed as neuroendocrine carcinoma originating from the apocrine glands of the anal sac.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21908338/