Peer-reviewed veterinary case report
Dog with cough and bleeding found to have neuroendocrine tumor
By Gould, E N et al.·Published in Journal of comparative pathology·2013·William R. Pritchard Veterinary Medical Teaching Hospital, United States·View original on PubMed →
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Original publication title: Neuroendocrine tumour at the carina of a dog.
- Species:
- dog
Plain-English summary
A 10-year-old female pit bull was brought to the vet because she was coughing, coughing up blood, and having trouble breathing. X-rays showed a mass in her chest, and a bronchoscopy (a procedure to look inside the airways) revealed a large tumor blocking her airways. The tumor was identified as a neuroendocrine tumor, which is a type of cancer that can affect hormone-producing cells. Treatment options would typically include surgery or other therapies, but the specific outcome for this dog was not mentioned.
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Abstract
A 10-year-old, neutered female, crossbred pit bull terrier was presented for cough, haemoptysis and rapidly progressive respiratory difficulty. Thoracic radiographs suggested a soft tissue density at the carina and bronchoscopy revealed a large, broad-based mass obstructing the entire left mainstem bronchus and half of the entrance to the right mainstem bronchus. Microscopically, the mass consisted of neoplastic cells that were packeted into small nests and had strong granular cytoplasmic immunoreactivity to synaptophysin and chromogranin A. Cytoplasmic neurosecretory granules stained strongly by the Grimelius method. A diagnosis of obstructive neuroendocrine tumour was made.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23582972/