Peer-reviewed veterinary case report
Neurologic and skin infection in a kitten with Tyzzer disease
By Oliveira, Eric S et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2023·Programa de Pó, Brazil·View original on PubMed →
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Original publication title: Neurologic and cutaneous infection byin a kitten with systemic Tyzzer disease.
- Species:
- cat
Plain-English summary
A young shelter kitten was brought in showing signs of severe illness, including skin sores and neurological issues. The kitten was diagnosed with Tyzzer disease, a serious infection that can affect multiple organs, along with a coinfection of feline panleukopenia virus. The veterinary team found that the kitten had severe intestinal and liver damage, as well as skin infections. Unfortunately, due to the severity of the disease, the kitten's prognosis was poor, and it did not survive.
People also search for: kitten skin sores · Tyzzer disease in cats · feline panleukopenia virus symptoms · cat neurological issues · kitten infection treatment
Abstract
Tyzzer disease (TD) is a highly fatal condition of animals caused byand characterized pathologically by enteritis, hepatitis, myocarditis, and occasionally encephalitis. Cutaneous lesions have been reported only rarely in animals with TD, and infection of the nervous system has not been described in cats, to our knowledge. We describe here neurologic and cutaneous infection byin a shelter kitten with systemic manifestations of TD and coinfection with feline panleukopenia virus. Systemic lesions included necrotizing typhlocolitis, hepatitis, myocarditis, and myeloencephalitis. The cutaneous lesions consisted of intraepidermal pustular dermatitis and folliculitis, with necrosis of keratinocytes and ulceration. Clostridial bacilli were identified within the cytoplasm of keratinocytes by fluorescence in situ hybridization, and a PCR assay was positive forcan infect keratinocytes leading to cutaneous lesions in cats with the location suggesting direct contact with contaminated feces as a route of infection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36896670/