Peer-reviewed veterinary case report
Neurological syndrome in goats associated with Ipomoea trifida and Ipomoea carnea containing calystegines.
- Journal:
- Toxicon : official journal of the International Society on Toxinology
- Year:
- 2019
- Authors:
- Salinas, Luis Manuel et al.
- Affiliation:
- Universidad Internacional Antonio de Valdivieso (UNIAV) · Spain
Abstract
A disease characterized by ataxia, tremors and nystagmus had been observed in goats in Nicaragua. The main histologic lesions were loss and neuronal vacuolation of Purkinje cells and Wallerian-like degeneration mainly in the cerebellum, suggesting a glycoprotein storage disease. Ipomoea carnea and Ipomoea trifida found in the paddocks were negative for swainsonine, but contained calystegines at 0.02% and 0.06% suggesting that the disease was caused by these substances, which are competitive inhibitors of β-glucosidase and α-galactosidase activities.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30447273/