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Peer-reviewed veterinary case report

Dog with B-cell lymphoma causing paralysis in left leg nerve

By Schaffer, P A et al.·Published in Veterinary pathology·2012·Colorado State University, United States·View original on PubMed

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Original publication title: Neurolymphomatosis in a dog with B-cell lymphoma.

Species:
dog

Plain-English summary

A 10-year-old English Cocker Spaniel was brought in with complete paralysis of the left back leg due to lymphoma affecting the femoral nerve. The cancerous cells were also found in several lymph nodes and one kidney, but the bone marrow was not affected. Unfortunately, this condition is quite serious and can be challenging to treat. The dog may require specialized care and treatment options, including chemotherapy, to manage the lymphoma and its effects on mobility.

People also search for: dog leg paralysis lymphoma treatment · English Cocker Spaniel cancer symptoms · dog nerve problems from lymphoma

Abstract

Lymphoma in the left femoral nerve of a 10-year-old English Cocker Spaniel caused complete paralysis of the affected limb. Neoplastic cells were immunopositive for CD79a and Pax5 and negative for CD3. Neoplastic cells were in multiple lymph nodes and one kidney but spared bone marrow. The clinical and histologic features in this case resemble those of the rare human condition of neurolymphomatosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21900543/