Peer-reviewed veterinary case report
Neuromuscular block effects of cisatracurium in cats during eye
By Van Wijnsberghe, Anne-Sophie et al.·Published in Journal of feline medicine and surgery·2022·Department of Anaesthesia and Resuscitation·View original on PubMed →
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Original publication title: Neuromuscular blockade effects of cisatracurium in 11 cats undergoing ophthalmological surgery anaesthetised with isoflurane.
- Species:
- cat
Plain-English summary
Eleven cats undergoing eye surgery were given a medication called cisatracurium to help relax their muscles during anesthesia. The cats, aged around 6 years and weighing about 4 kg, showed varying levels of muscle relaxation, with some achieving complete relaxation while others did not. The medication took effect within 1 to 6 minutes and lasted for about 20 minutes on average. Importantly, the treatment did not cause any significant heart problems, and it successfully helped position the eyes as needed for the surgeries.
People also search for: cat eye surgery anesthesia · cisatracurium for cats · muscle relaxant for cat surgery
Abstract
CASE SERIES SUMMARY: This case series describes the neuromuscular blockade (NMB) following 0.15 mg/kg intravenous (IV) cisatracurium administration in 11 cats undergoing ophthalmological surgery and anaesthetised with isoflurane. Anaesthetic records were analysed retrospectively. Neuromuscular function was assessed by a calibrated train-of-four (TOF) monitor. Cats were 73 ± 53 months old, weighed 4 ± 1 kg and were of American Society of Anesthesiologists' physical classification 2. Duration of anaesthesia and surgery were 144 ± 27 and 94 ± 24 mins, respectively. The lowest TOF count was zero in four cats, four in six cats and for one cat the TOF ratio never decreased below 31%. The time of onset was between 1 and 6 mins after the administration of cisatracurium and the mean duration of action was 20.4 ± 10.1 mins. RELEVANCE AND NOVEL INFORMATION: Cisatracurium at a dose of 0.15 mg/kg IV did not consistently induce a TOF count of zero in all cats. The dose used in these cats did not produce any remarkable cardiovascular side effects. Although the NMB was not complete, the dose given was sufficient to produce central eyeball position, which was the goal of the ophthalmic surgeries.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34152242/