Peer-reviewed veterinary case report
Neuroprotection and secondary damage following spinal cord injury: concepts and methods.
- Journal:
- Neuroscience letters
- Year:
- 2017
- Authors:
- Hilton, Brett J et al.
- Affiliation:
- University of British Columbia · Canada
Abstract
Neuroprotection refers to the attenuation of pathophysiological processes triggered by acute injury to minimize secondary damage. The development of neuroprotective treatments represents a major goal in the field of spinal cord injury (SCI) research. In this review, we discuss the strengths and limitations of the methodologies employed to assess secondary damage and neuroprotection in preclinical models of traumatic SCI. We also discuss modelling issues and how new tools might be exploited to study secondary damage and neuroprotection.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27939975/