Peer-reviewed veterinary case report
Rabies vaccine antibody response in dogs and cats after inoculation
By Shiraishi, Rikiya et al.·Published in The Journal of veterinary medical science·2014·Research Institute for Animal Science in Biochemistry & Toxicology, Japan·View original on PubMed →
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Original publication title: Neutralizing antibody response in dogs and cats inoculated with commercial inactivated rabies vaccines.
Plain-English summary
A study in Japan found that dogs and cats vaccinated against rabies can maintain the necessary levels of protective antibodies for a long time if they receive their vaccinations on schedule. However, if blood tests to check these antibody levels are done too soon after vaccination, the results might show lower levels than actually present. This means that timing is important to ensure pets are properly protected against rabies when traveling. Keeping up with regular vaccinations is key to ensuring your pet's safety.
People also search for: dog rabies vaccine effectiveness · cat rabies vaccination schedule · how long does rabies vaccine last in dogs
Abstract
In Japan, the import quarantine regulation against rabies has required from 2005 that dogs and cats should be inoculated with the rabies vaccine and that the neutralizing antibody titer should be confirmed to be at least 0.5 international units (IU)/ml. The fluorescent antibody virus neutralization (FAVN) test is used as an international standard method for serological testing for rabies. To achieve proper immunization of dogs and cats at the time of import and export, changes in the neutralizing antibody titer after inoculation of the rabies vaccine should be understood in detail. However, few reports have provided this information. In this study, we aimed to determine evaluated, such changes by using sera from experimental dogs and cats inoculated with the rabies vaccine, and we tested samples using the routine FAVN test. In both dogs and cats, proper, regular vaccination enabled the necessary titer of neutralizing antibodies to be maintained in the long term. However, inappropriate timing of blood sampling after vaccination could result in insufficient detected levels of neutralizing antibodies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24389741/