Peer-reviewed veterinary case report
Neutropenia in dogs and cats: a retrospective study of 261 cases.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 2001
- Authors:
- Brown, M R & Rogers, K S
- Affiliation:
- Department of Small Animal Medicine and Surgery · United States
- Species:
- cat
Plain-English summary
In a study of 261 pets, including 232 dogs and 29 cats, researchers looked into the reasons why these animals had low white blood cell counts, a condition known as neutropenia. They found several causes, with the most common being nonbacterial infections, such as parvovirus, which was responsible for nearly half of the cases. Other causes included severe inflammation, infections from bacteria, reactions to medications, diseases affecting the bone marrow, and immune system issues. The least common cause was a naturally occurring immune problem that led to neutropenia. Overall, the study highlights the importance of identifying the underlying cause of neutropenia in pets to guide treatment.
Abstract
Case records of 232 dogs and 29 cats with neutropenia were reviewed to examine the spectrum of underlying etiologies causing the neutropenia. Six etiological categories included nonbacterial infectious disease; increased demand due to marked inflammation, bacterial sepsis, or endotoxemia; drug-associated neutropenia; primary bone-marrow disease; immune-mediated neutropenia; and diseases of unclear etiology. The largest single category associated with the development of neutropenia was nonbacterial infectious disease (e.g., feline leukemia virus [FeLV], feline immunodeficiency virus [FIV], histoplasmosis, cryptococcosis, and parvovirus), with parvovirus infection accounting for 47.1% of all cases. The least common (0.38%) cause was naturally occurring immune-mediated neutropenia.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/11300519/