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Peer-reviewed veterinary case report

Dog with facial swelling and skin ulcers like pyoderma gangrenosum

By Bardagí, M et al.·Published in The Journal of small animal practice·2007·Department of Animal Medicine & Surgery and Veterinary Teaching Hospital, Spain·View original on PubMed

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Original publication title: Neutrophilic dermatosis resembling pyoderma gangrenosum in a dog with polyarthritis.

Species:
dog

Plain-English summary

A 7-year-old female German Shepherd was brought in with severe facial swelling and painful sores on her muzzle and body. After testing, the vet found no infections but diagnosed her with a rare skin condition similar to pyoderma gangrenosum, which is characterized by inflammation and skin lesions. The dog responded very well to treatment with prednisone and ciclosporin, leading to significant improvement in her condition.

People also search for: dog skin sores treatment · German Shepherd facial swelling · prednisone for dog skin problems

Abstract

This report describes a case of neutrophilic dermatosis in a dog, with a number of clinical and pathological similarities to human pyoderma gangrenosum. A seven-year-old, female German shepherd dog with a history of non-erosive idiopathic polyarthritis was presented with severe facial swelling, bilateral erosivoulcerative lesions on the muzzle and multiple, eroded, dermal-subcutaneous nodules on the cranial trunk. Histopathological examination of skin biopsies revealed a necrotising neutrophilic dermatitis. No infectious agents could be detected using specific stains, immunohistochemistry, serology and bacterial aerobic, anaerobic or fungal cultures. A sterile neutrophilic dermatosis resembling human pyoderma gangrenosum was presumptively diagnosed, and the patient showed an excellent response to treatment with prednisone and ciclosporin.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17381769/