Peer-reviewed veterinary case report
Dog with rectal tumor and high neutrophil count treated with piroxicam
By Knottenbelt, C M et al.·Published in The Journal of small animal practice·2000·Department of Veterinary Clinical Studies·View original on PubMed →
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Original publication title: Neutrophilic leucocytosis in a dog with a rectal tumour.
- Species:
- dog
Plain-English summary
A 9-year-old cocker spaniel was brought in for bleeding from the rectum and a noticeable mass in the rectum that had been present for three years. Tests showed a high level of white blood cells, indicating an infection or inflammation. A colonoscopy revealed a polyp, which was found to have some signs of cancer. The vet started treatment with piroxicam suppositories, which helped reduce the bleeding and discomfort after about seven weeks, although the dog's bathroom habits stayed the same. The neutrophil count also decreased, showing a positive response to the treatment.
People also search for: dog rectal bleeding · cocker spaniel rectal tumor treatment · piroxicam for dogs
Abstract
A nine-year-old cocker spaniel was presented with a three-year history of intermittent haematochezia and a palpable rectal mass. Routine haematological examination revealed a marked mature neutrophilia (86.04 x 10(9) neutrophils/litre). A friable mass in the middle portion of the rectum was detected on colonoscopy. Histopathological examination of mucosal pinch biopsies collected from the mass confirmed a diagnosis of adenomatous tubulopapillary polyp. Some evidence of malignant transformation was observed. Palliative treatment with piroxicam suppositories at a dose of 1.4 mg/kg administered rectally every third day was instituted. On re-evaluation, 47 days after starting medical therapy, the owner reported a significant reduction in haematochezia and tenesmus; however, frequency of defecation had remained unaltered. Routine haematology revealed a reduction in the mature neutrophil count (33.67 x 10(9) neutrophils/litre). This report describes a case of a rectal tumour associated with a neutrophilic leucocytosis, which responded to palliative therapy with piroxicam suppositories.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11072914/