Peer-reviewed veterinary case report
New Copper(I) Complex with a Coumarin as Ligand with Antibacterial Activity against.
- Journal:
- Molecules (Basel, Switzerland)
- Year:
- 2020
- Authors:
- Aldabaldetrecu, Maialen et al.
- Affiliation:
- Faculty of Chemistry and Biology
Abstract
A new copper (I) complex, [Cu(NN)](ClO)was synthesized, where NNwas a imine ligand 6-((quinolin-2-ylmethylene)amino)-2H-chromen-2-one obtained by a derivatization of natural compound coumarin. The structural characterization in solution was done by NMR techniques, UV-Vis and cyclic voltammetry. The potential antibacterial effect of [Cu(NN)](ClO)was assessed forisolated 10094.is a Gram-negative bacterium which causes diseases such as bacterial cold-water disease and rainbow trout fry syndrome, causing large economic losses in the freshwater salmonid aquaculture industry. This complex show to have antibacterial activity against10094 at non-cytotoxic concentration in cell line derived from trout (10094 IC16.0 ± 0.9; RT-GUT IC53.0 ± 3.1 µg/mL).
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32668579/