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Peer-reviewed veterinary case report

Nfkbid-mediated humoral immunity during secondary toxoplasmosis.

Journal:
Trends in parasitology
Year:
2022
Authors:
Khan, Imtiaz A & Moretto, Magali
Affiliation:
Department of Microbiology · United States
Species:
rodent

Abstract

Vaccine-mediated immunity to parasites has not been achieved. Immune C57BL/6 mice are susceptible to secondary Toxoplasma gondii infection. Using a forward genetics approach, Souza et al. identify Nfkbid as an important factor for the regulation of B cell immunity during secondary Toxoplasma infection and protection against rechallenge.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/35190281/