Peer-reviewed veterinary case report
NMDA receptor antagonist MK-801 infused into the insular cortex prevents the attenuation of gustatory neophobia in rats.
- Journal:
- Brain research
- Year:
- 2006
- Authors:
- Figueroa-Guzmán, Yazmín et al.
- Affiliation:
- Department of Psychology · United States
- Species:
- rodent
Abstract
Gustatory neophobia dissipates with repeated exposures to an initially novel taste solution. The aim of the present study was to determine whether NMDA receptors in the insular cortex are involved in this experience-dependent process. Results showed that acute microinfusion of MK-801 into the insular cortex prevented the attenuation of gustatory neophobia indicating that this process is an NMDA receptor-dependent phenomenon.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16935274/