Peer-reviewed veterinary case report
No effect of bovine interferon-tau for control of calf diarrhea and immunomodulation in calves.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2004
- Authors:
- Kohara, Junko et al.
- Affiliation:
- Hokkaido Animal Research Center · Japan
Abstract
Newborn calves received a low dose of bovine interferon-tau (boIFN-tau) orally for 4 weeks and calves that had developed diarrhea received a low dose of boIFN-tau orally for 5 days. No effects of boIFN-tau were seen in the duration of the diarrhea, or in daily weight gain. Calves received a high dose of boIFN-tau subcutaneously 3 times and they were then stimulated with bovine herpesvirus type 1 vaccine. No adverse effects were observed after the administration of boIFN-tau and lymphocyte subsets from calves did not change after the stimulation. Our results suggest that boIFN-tau does not seem protecting for preventing calves from diarrhea, recovering the health of calves with diarrhea or immunomodulation, although the treatment itself is not toxic.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15472487/