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Peer-reviewed veterinary case report

Atopic dogs showed skin improvement on grain free and standard diets

By Verde, María Teresa et al.·Published in The veterinary quarterly·2023·Animal Pathology Department, Spain·View original on PubMed

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Original publication title: Non-controlled, open-label trial to assess clinical and immunological parameters in atopic dogs feeding monoprotein grain free dieta standard grain diet.

Species:
dog

Plain-English summary

A group of dogs with atopic dermatitis (a common skin condition causing itching and inflammation) were fed two different diets to see which one helped their symptoms more. One diet was grain-free and rich in salmon, while the other was based on rice. After 30 days, both diets showed improvements in skin scores, but the rice-based diet also reduced overall itchiness. While the diets didn't significantly change certain immune markers, the rice diet did lead to better levels of specific proteins related to inflammation. This suggests that diet can play a role in managing skin issues in dogs, but more research is needed to find the best options.

People also search for: dog skin problems diet · atopic dermatitis treatment for dogs · grain-free diet for itchy dogs

Abstract

Canine atopic dermatitis (cAD) is a common inflammatory skin disease that is treated with medicines or allergen-specific immunotherapy. An improvement diet can help treatment of cAD. The purpose of this study was compare two diets on clinical and immunological parameters in atopic dogs without food hypersensitivity. Diet A, a commercial based on rice, was offered to 22 atopic dogs during 30&#x2009;days and Diet B (grain free, rich in salmon) was given to 8 atopic dogs. Clinical scores were assessed by CADESI-4 and PVAS at the beginning (T0) and at the end of the study (T30). CD4and CD8were measured in PBMCs, and serum cytokines (TNF-&#x3b1;, IL-10, IL-31 and IL-34) were determined. Both diets decreased CADESI-4 score and Diet A decreased PVAS score (&#x2009;<&#x2009;0.05). There were no statistical significant differences between diets at T30 for CD4and CD8. A decrease in the IL-31 concentrations and increase in IL-10 levels (&#x2009;<&#x2009;0.05) was observed with Diet A at T30. There were no differences between any of the two diets when the other results at T0 and T30 were compared for any of the parameters analysed. In conclusion, the results indicate that dietary intervention had not influence on cellular component of the immune system, but a positive effect was observed on IL-31, IL-10 serum levels for Diet A. Further studies are needed to enrich dietary components of the food for atopic dogs without food hypersensibility to help improvement the management of the cAD.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37530035/