Peer-reviewed veterinary case report
Non-typhoidal Salmonella encephalopathy involving lipopolysaccharide in cattle.
- Journal:
- Veterinary microbiology
- Year:
- 2013
- Authors:
- Xiong, N et al.
- Affiliation:
- Department of Biomedical Sciences · United States
Abstract
This study assessed the involvement of lipopolysaccharide (LPS) in the non-typhoidal Salmonella encephalopathy (NTSE) caused by a unique isolate of Salmonella enterica serovar Saint-paul (SstpNPG). NTSE was prevented by genetic (deletion of murE) or pharmacologic (polymyxin) disruption of LPS on SstpNPG although the disruption of LPS did not deter brain penetration of the strain. This is the first study to demonstrate that LPS is involved in the manifestations of NTSE.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22939987/