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Peer-reviewed veterinary case report

Rottweiler with duodenal ulcer and perforation from NSAIDs

By Reed, Suma·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2002·Western College of Veterinary Medicine, Canada·View original on PubMed

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Original publication title: Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler.

Species:
dog

Plain-English summary

A mature male Rottweiler suddenly collapsed and showed signs of severe abdominal pain. After a thorough examination, the veterinarian found a large perforated ulcer in the dog's upper intestine, which was likely caused by the combination of two pain medications, meloxicam and aspirin. This condition led to a serious infection in the abdomen. The dog required surgery to repair the ulcer and treat the infection.

People also search for: Rottweiler abdominal pain · dog ulcer treatment · meloxicam aspirin side effects

Abstract

A mature male rottweiler was evaluated for acute collapse and abdominal pain. The history consisted of concurrent administration of meloxicam and aspirin. On exploratory laparotomy, a large perforated ulcer was discovered in the proximal duodenum, with secondary peritonitis. The pathogenesis of NSAID-induced gastrointestinal ulceration and the supposed safety of COX-2 selective agents are discussed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12561693/