Peer-reviewed veterinary case report
Novel bivalent vectored vaccine for control of myxomatosis and rabbit haemorrhagic disease
- Journal:
- Veterinary Record
- Year:
- 2012
- Authors:
- Spibey, N. et al.
- Affiliation:
- MSD Animal Health Milton Keynes UK · United Kingdom
- Species:
- rabbit
Plain-English summary
Researchers have created a new vaccine that helps protect rabbits from two serious diseases: myxomatosis and rabbit hemorrhagic disease (RHD). In laboratory studies, they tested this vaccine on rabbits starting at four weeks old. The vaccinated rabbits were exposed to the viruses that cause these diseases, and all of them were successfully protected from getting sick. This means the vaccine appears to be very effective and safe for use in rabbits.
Abstract
A novel, recombinant myxoma virus‐rabbit haemorrhagic disease virus (RHDV) vaccine has been developed for the prevention of myxomatosis and rabbit haemorrhagic disease (RHD). A number of laboratory studies are described illustrating the safety and efficacy of the vaccine following subcutaneous administration in laboratory rabbits from four weeks of age onwards. In these studies, both vaccinated and unvaccinated control rabbits were challenged using pathogenic strains of RHD and myxoma viruses, and 100 per cent of the vaccinated rabbits were protected against both myxomatosis and RHD.
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Search related cases →Original publication: https://doi.org/10.1136/vr.100366