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Peer-reviewed veterinary case report

Dog with symmetrical brain lesions from two types of encephalitis

By Procter, Tessa Victoria et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2026·The Royal (Dick) School of Veterinary Studies, United Kingdom·View original on PubMed

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Original publication title: Novel Magnetic Resonance Imaging Findings of Bilaterally Symmetrical Lesions in a Dog With Concomitant Granulomatous Meningoencephalitis and Necrotizing Encephalitis.

Species:
dog
Brain & nervesDogs

Plain-English summary

A 3-year-old female Bichon Frise was brought to the vet after showing unusual behavior and difficulty walking for two days. An MRI revealed abnormal brain lesions that were affecting her movement and behavior. Further tests showed she had two serious brain conditions: granulomatous meningoencephalitis and necrotizing encephalitis, which are types of inflammation in the brain. Treatment options for these conditions can vary, and it's important to discuss with your veterinarian the best approach for managing her symptoms and improving her quality of life.

People also search for: dog behavioral changes · Bichon Frise ataxia · dog brain inflammation treatment

Abstract

A 3-year-old, female neutered Bichon Frise was presented with a 2-day history of behavioral changes and ataxia. The neurological examination was consistent with diffuse forebrain involvement, with left lateralization. An MRI study identified bilaterally symmetrical T2W/T2 fluid-attenuated inversion recovery (T2-FLAIR) hyperintense, T1W hypointense, non-enhancing lesions involving the basal nuclei, with restricted diffusion and hemorrhage affecting both caudate nuclei. Similar bilaterally symmetrical T2W/T2-FLAIR hyperintense lesions were noted in the hypothalamus, midbrain, and occipital lobes. Histopathological examination indicated concomitant granulomatous meningoencephalitis and necrotizing encephalitis. This case report documents previously unreported bilaterally symmetrical canine brain lesions suspected to be secondary to an autoimmune inflammatory etiology.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41392748/