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Peer-reviewed veterinary case report

Novel polyomavirus detected in the feces of a chimpanzee by nested broad-spectrum PCR.

Journal:
Journal of virology
Year:
2005
Authors:
Johne, Reimar et al.
Affiliation:
Institute for Virology · Germany

Abstract

In order to screen for new polyomaviruses in samples derived from various animal species, degenerated PCR primer pairs were constructed. By using a nested PCR protocol, the sensitive detection of nine different polyomavirus genomes was demonstrated. The screening of field samples revealed the presence of a new polyomavirus, tentatively designated chimpanzee polyomavirus (ChPyV), in the feces of a juvenile chimpanzee (Pan troglodytes). Analysis of the region encoding the major capsid protein VP1 revealed a unique insertion in the EF loop of the protein and showed that ChPyV is a distinct virus related to the monkey polyomavirus B-lymphotropic polyomavirus and the human polyomavirus JC polyomavirus.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15731285/