Peer-reviewed veterinary case report
Diet changes lower urine calcium and oxalate in stone-forming dogs
By Stevenson, Abigail E et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2004·The Waltham Centre for Pet Nutrition, United Kingdom·View original on PubMed →
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Original publication title: Nutrient intake and urine composition in calcium oxalate stone-forming dogs: comparison with healthy dogs and impact of dietary modification.
- Species:
- dog
Plain-English summary
A group of dogs that formed calcium oxalate stones had different nutrient intakes compared to healthy dogs, showing lower levels of sodium, calcium, potassium, and phosphorus. After switching to a special diet designed for urinary tract health for one month, these dogs increased their moisture, sodium, and fat intake while reducing potassium and calcium. This dietary change led to lower levels of calcium and oxalate in their urine, and importantly, none of the dogs showed signs of stone recurrence over the next 11 months. This suggests that adjusting their diet can help prevent future stone formation.
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Abstract
Nutrient intake and urine composition were analyzed in calcium oxalate (CaOx)stone-forming and healthy control dogs to identify factors that contribute to CaOx urolithiasis. Stone-forming dogs had significantly lower intake of sodium, calcium, potassium, and phosphorus and significantly higher urinary calcium and oxalate concentrations, calcium excretion, and CaOx relative supersaturation (RSS). Feeding a diet used in the treatment of canine lower urinary tract disease for 1 month was associated with increased intake of moisture, sodium, and fat; reduced intake of potassium and calcium; and decreased urinary calcium and oxalate concentrations, calcium excretion, and CaOx RSS. No clinical signs of disease recurrence were observed in the stone-forming dogs when the diet was fed for an additional 11 months. The results suggest that hypercalciuria and hyperoxaluria contribute to the formation of CaOx uroliths in dogs and show that dietary modifications can alter this process.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15578454/