Peer-reviewed veterinary case report
Clindamycin resistance found in methicillin-resistant Staphylococcus
By Chanchaithong, Pattrarat & Prapasarakul, Nuvee·Published in Veterinary journal (London, England : 1997)·2016·Department of Veterinary Microbiology·View original on PubMed →
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Original publication title: Occurrence and characterization of inducible clindamycin resistance in canine methicillin-resistant Staphylococcus pseudintermedius.
- Species:
- dog
Plain-English summary
A study found that 17% of dogs tested in Thailand had a type of bacteria called methicillin-resistant Staphylococcus pseudintermedius (MRSP) that was resistant to clindamycin, an antibiotic often used to treat skin infections. This resistance was identified in 10 out of 200 samples taken from dogs, indicating a concerning trend of multidrug resistance. The researchers recommend a specific test called D-zone testing to help veterinarians choose the right antibiotics and manage these resistant infections effectively.
People also search for: dog skin infection treatment · clindamycin resistance in dogs · MRSP in dogs · antibiotic resistance in pets
Abstract
This study aimed to detect inducible clindamycin (iCLI) resistance in Staphylococcus pseudintermedius isolated from dogs in Thailand using D-zone testing. Strains that were iCLI-resistant were characterized by molecular typing and antibiogram and were detected in 10/200 S. pseudintermedius isolates (5%) from 7/41 dogs (17%). All were methicillin-resistant S. pseudintermedius (MRSP) and demonstrated multidrug resistance. The iCLI-resistant MRSP contained erm(B) and had identical or closely related DNA fingerprint patterns by pulsed-field gel electrophoresis. All iCLI-resistant MRSP strains belonged to the same clonal complex 112 (sequence types 111 and 112) by multilocus sequence typing. To avoid misinterpretation of clindamycin susceptibility, D-zone testing is recommended to promote rational antimicrobial selection and limit the clonal expansion of multidrug resistant bacteria.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26616424/