Peer-reviewed veterinary case report
Severe diarrhea in puppies after parvovirus vaccine and infection
By Decaro, Nicola et al.·Published in Vaccine·2007·Department of Animal Health and Well-being, Italy·View original on PubMed →
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Original publication title: Occurrence of severe gastroenteritis in pups after canine parvovirus vaccine administration: a clinical and laboratory diagnostic dilemma.
- Species:
- dog
Plain-English summary
A group of puppies developed severe diarrhea after receiving the canine parvovirus vaccine. Tests showed that most of these cases were due to a wild strain of the virus rather than a reaction to the vaccine itself. In fact, while some puppies had the vaccine strain, they also tested positive for other infections. This suggests that if your puppy has diarrhea after vaccination, it’s more likely due to an infection they picked up rather than the vaccine causing the problem.
People also search for: puppy diarrhea after parvovirus vaccine · canine parvovirus symptoms · dog vaccination side effects
Abstract
A total of 29 faecal samples collected from dogs with diarrhoea following canine parvovirus (CPV) vaccination were tested by minor groove binder (MGB) probe assays for discrimination between CPV vaccine and field strains and by diagnostic tests for detection of other canine pathogens. Fifteen samples tested positive only for CPV field strains; however, both vaccine and field strains were detected in three samples. Eleven samples were found to contain only the vaccine strain, although eight of them tested positive for other pathogens of dogs. Only three samples were found to contain the vaccine strain without evidence of canine pathogens. The present study confirms that most cases of parvovirus-like disease occurring shortly after vaccination are related to infection with field strains of canine parvovirus type 2 (CPV-2) rather than to reversion to virulence of the modified live virus contained in the vaccine.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17092616/