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Peer-reviewed veterinary case report

Cat with eye inflammation caused by leishmaniasis in Brazil

By G. Madruga et al.·Published in Arquivo Brasileiro de Medicina Veterinária e Zootecnia·View original on DOAJ

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Original publication title: Ocular manifestations of leishmaniasis in a cat: first case report from Brazil

Species:
cat

Plain-English summary

An 8-year-old female domestic short hair cat was brought to the vet with eye problems, specifically bilateral uveitis that looked like a tumor. After testing negative for common viruses and parasites, the vet found signs of Leishmania infection in a tissue sample from her eye. The cat was treated with allopurinol, a medication that helps manage the infection, along with a natural insect repellent. After six months of treatment, her eye symptoms improved significantly.

People also search for: cat eye problems · cat uveitis treatment · Leishmania in cats · allopurinol for cats · cat eye infection symptoms

Abstract

ABSTRACT An 8-year-old domestic short hair female cat initially presented with bilateral uveitis with pseudotumoral appearance. The patient tested negative for feline immunodeficiency virus (FIV), feline leukemia virus (FeLV) and Toxoplasma gondii. Histopathology of a granulomatous lesion on the upper left conjunctiva revealed amastigotes compatible with Leishmania spp. Aqueous humor was aspired and the diagnosis was confirmed after isolation of promastigotes cultivated in biphasic NNN medium and by positive polymerase chain reaction (PCR) for Leishmania infantum. Treatment with allopurinol (10mg/kg/ BID/PO) was commenced and a natural insect repellent was prescribed. Six months of treatment with allopurinol associated with the initial topical medications helped to improve ocular signs. Leishmaniasis should be considered as a differential diagnosis in cats presenting uveitis with pseudotumoral appearance. To our knowledge, this is the first report of feline leishmaniasis with ocular manifestation in Brazil, in which diagnosis was confirmed by aqueous humor analysis.

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Original publication on DOAJ: https://doi.org/10.1590/1678-4162-9244