Peer-reviewed veterinary case report
Vision loss and short legs in Labrador Retrievers with oculo-skeletal
By Sebbag, Lionel et al.·Published in Veterinary Ophthalmology·2019·Department of Veterinary Clinical Sciences Iowa State University College of Veterinary Medicine Ames Iowa·View original on Crossref →
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Original publication title: Oculo‐skeletal dysplasia in five Labrador Retrievers
- Species:
- dog
Plain-English summary
Five Labrador Retrievers were diagnosed with oculo-skeletal dysplasia (OSD), a genetic condition that caused them to have vision problems and short limbs. All dogs showed signs of cataracts and other eye issues, as well as skeletal abnormalities like elbow and hip problems. Some dogs required cataract surgery as their condition worsened over time. Regular check-ups are important for monitoring the progression of these issues.
People also search for: Labrador Retriever vision problems · dog cataract surgery · oculo-skeletal dysplasia in dogs · Labrador Retriever short limbs · dog eye problems
Abstract
AbstractObjectiveTo describe the clinical features and diagnostic findings of Labrador Retrievers with oculo‐skeletal dysplasia (OSD).Animal studiedFive privately owned dogs.ProceduresMedical records of dogs diagnosed with OSD from 2008 through 2018 were reviewed. Patients were excluded if lacking disease confirmation through genetic testing (Optigen RD/OSD). Information collected included signalment, physical and ophthalmic examination findings, results of ocular ultrasound and electroretinogram, and digital radiographs of forelimbs and pelvis.ResultsAll five dogs were Labrador Retrievers, confirmed to be homozygote for the OSD mutation. The main physical abnormalities were vision deficits (5 dogs), short‐limbed dwarfism (5), carpal valgus (4), and color dilution alopecia (4). The main ophthalmic anomalies were cataracts (10 eyes), vitreous syneresis (10), retinal separation (6), persistent hyperplastic primary vitreous (2), lens coloboma (2), microphakia (2), and persistent tunica vasculosa lentis (1). Ocular ultrasound and electroretinogram confirmed the diagnoses of retinal separations and persistent hyperplastic primary vitreous. Radiographic changes included shortening of ulna and curved radius (5 dogs), elbow incongruity and osteoarthritis (4 dogs), hip dysplasia (3), and coxofemoral osteoarthritis (2). Available follow‐up information (2 dogs) showed progression of cataract from incipient to mature in one dog, necessitating cataract surgery, and progression of cataract and lameness in another dog.ConclusionsThe clinical findings of OSD are described in five Labrador Retrievers. DNA testing is critical to diagnose OSD and help eradicate this condition from the breed. Progression of cataracts and osteoarthritis in dogs with OSD warrants yearly monitoring.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/vop.12715