Peer-reviewed veterinary case report
Esophageal sarcoma tumor types and survival after surgery in dogs
By Ranen, Eyal et al.·Published in Veterinary journal (London, England : 1997)·2008·School of Veterinary Medicine·View original on PubMed →
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Original publication title: Oesophageal sarcomas in dogs: histological and clinical evaluation.
- Species:
- dog
Plain-English summary
A group of dogs with oesophageal sarcomas (a type of cancer in the esophagus) was studied to understand their tumor characteristics and outcomes. Out of 32 dogs, 19 had surgery to remove the tumors, and 10 of those dogs lived for an average of about 9 months after the surgery. The tumors varied, with the most common being osteosarcoma, and the study found that while surgery was the best treatment, chemotherapy showed promise in reducing lung metastases in some cases. More research is needed to better understand these tumors and improve treatment options.
People also search for: dog esophageal cancer treatment · oesophageal sarcoma in dogs · dog cancer survival rates · chemotherapy for dog tumors · signs of cancer in dogs
Abstract
A histological grading system of oesophageal sarcomas has not been established. Thirty-two cases of oesophageal sarcomas have been reviewed for tumour characteristics and clinical outcome. Nineteen dogs underwent surgical intervention to remove oesophageal tumours; ten of them survived (median 278 days). Primary tumour types included osteosarcoma (47%), osteosarcoma with tumour giant cells (7%), fibroblastic osteosarcoma (13%), chondroblastic osteosarcoma (7%) fibrosarcoma (23%) and undifferentiated sarcoma (3%). Histological grade evaluation revealed 33% grade 1 sarcoma, 50% grade 2 and 17% grade 3. No correlation could be found between survival and signalment, duration of clinical signs, tumour type, tumour grade and chemotherapy. Chemotherapy was found to reduce lung metastases' histological scores in three cases (P=0.0007). Surgery seems to be the treatment of choice but the effect of chemotherapy warrants further investigation. Additional research of cases should be performed in order to further define prognostic factors of oesophageal sarcomas.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17804268/