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Peer-reviewed veterinary case report

Dog with nasal tumor causing noisy breathing treated with radiation

By Ueno, H et al.·Published in Australian veterinary journal·2007·Department of Clinical Veterinary Science, Japan·View original on PubMed

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Original publication title: Olfactory esthesioneuroblastoma treated with orthovoltage radiotherapy in a dog.

Species:
dog

Plain-English summary

A 13-year-old female mongrel dog was having trouble breathing due to a mass in her nasal cavity, which was diagnosed as olfactory esthesioneuroblastoma, a type of tumor. She received radiation therapy over several weeks, which initially reduced the size of the tumor and improved her breathing. However, after a few months, the tumor grew back, and she underwent a second round of radiation treatment. Unfortunately, the tumor regrowth was detected again a few months later, indicating that this type of tumor can be challenging to manage.

People also search for: dog nasal tumor treatment · breathing problems in dogs · olfactory esthesioneuroblastoma in dogs · dog radiation therapy outcome

Abstract

A 13-year-old neutered female mongrel dog presented with a 1-year history of stertorous respiration. On computed tomography examination, a mass was demonstrated in the nasal cavity. Open biopsy of the mass was performed and a diagnosis of olfactory esthesioneuroblastoma was made on histological examination. The dog was treated with orthovoltage x-ray radiation (total dose; 53 Gy given in 14 fractions over an 8 week period). Computed tomography after the twelfth irradiation revealed that tumour size had decreased. Although clinical signs were absent in the 4 months after irradiation, re-growth of the tumour was detected by radiographic evaluation and histological examination. The dog was again treated with orthovoltage x-ray radiation (total dose; 30 Gy given in three fractions over a 4-week period), however, tumour regrowth was again detected 3 months later. Clinical treatment of this tumour type has not been previously reported.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17615040/