Peer-reviewed veterinary case report
Dog with nasal tumor causing snoring and nosebleeds case report
By Romano, Ashley M & Frank, Chad B·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2021·College of Veterinary Medicine and Biomedical Sciences, United States·View original on PubMed →
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Original publication title: Olfactory ganglioneuroblastoma in a dog: case report and literature review.
- Species:
- dog
Plain-English summary
A 7-year-old male Alaskan Malamute was brought to the vet because he had been snoring loudly and had nosebleeds for three months. A CT scan showed a mass in his nasal passages that was causing these symptoms. After testing the tissue, the vet found that the mass was made up of abnormal nerve cells, indicating a rare type of tumor called olfactory ganglioneuroblastoma. Unfortunately, the outcome for this dog isn't mentioned, but treatment options for similar cases may include surgery or other therapies.
People also search for: dog nosebleeds · Alaskan Malamute snoring · dog nasal tumor treatment
Abstract
A 7-y-old, intact male Alaskan Malamute was presented with a 3-mo history of stertor and epistaxis. Computed tomography of the skull revealed generalized loss of gas throughout both nasal passages with replacement by a soft tissue mass that traversed the cribriform plate. Histopathology revealed neoplastic neuroblast cells arranged in anastomosing cords, as well as separately located aggregates of ganglion cells. Both neoplastic cell populations demonstrated immunoreactivity to MAP-2, TuJ-1, and synaptophysin. Neuroblastic cells additionally exhibited punctate immunoreactivity to MCK and CK8/18. We document here both the positive neural immunohistochemical markers for this neoplasm, as well as propose possible histomorphologic variants.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34109889/