Peer-reviewed veterinary case report
Dog with nasal tumor causing nosebleeds and facial swelling studied
By Hara, Kazuya et al.·Published in The Journal of veterinary medical science·2002·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Olfactory neuroepithelioma in a dog: an immunohistochemical and electron microscopic study.
- Species:
- dog
Plain-English summary
A 10-year-old female dog was brought to the vet with nosebleeds, nasal discharge, and swelling on her face. After tests, the vet found a tumor in her nasal cavity called olfactory neuroepithelioma, which has both nerve and epithelial cell features. The tumor was made up of tightly packed cells and showed signs of rapid growth. Unfortunately, the abstract does not provide information on treatment or the outcome for this dog.
People also search for: dog nosebleed causes · nasal tumor in dogs · dog facial swelling treatment
Abstract
A case of olfactory neuroepithelioma was investigated electron microscopically and immunohistochemically. The tumor mass was found in the nasal cavities of a 10-year-old female dog, which showed epistaxis, nasal discharge and facial swelling. The tumor tissue consisted of tubular structure of cuboidal to columnar cells and compactly arranged nests of small cells surrounded by a fibrovascular stroma. Mitotic figures were frequently observed. Immunohistochemically, the tumor cells frequently showed positive for neurofilament protein, synaptophysin and/or carnosine in addition to keratin. Ultrastructurally, tight junction was observed between the tumor cells. No dense-cored secretory granules were shown in the tumor cells. These findings indicated that the present tumor had neuronal and epithelial features probably originating from the olfactory epithelium.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12014590/