Peer-reviewed veterinary case report
Brain tumor oligodendroglioma found in 5-year-old French bulldog
By Park, Chun-Ho·Published in Journal of veterinary science·2003·Department of Pathobiological Sciences, United States·View original on PubMed →
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Original publication title: Oligodendroglioma in a French bulldog.
- Species:
- dog
Plain-English summary
A 5-year-old male French bulldog was found to have serious health issues, including slow heart rate, breathing problems, and severe neurological symptoms. Sadly, after the dog passed away, a necropsy revealed a brain tumor called oligodendroglioma, which was a soft, grayish mass located in the brain. This type of tumor is made up of abnormal brain cells that can invade surrounding tissue. Unfortunately, due to the aggressive nature of the tumor, treatment options for recovery were not successful in this case.
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Abstract
A 5-year-old, male French bulldog with bradycardia, dyspnea, and decerebrate rigidity was necropsied. Macroscopic findings were restricted to the brain, and a single mass, 1.5 x 2.0 x 1.5 cm in size, was observed mainly at the right cingulum with prominently protruding into the dilated right lateral ventricle. The mass was grayish white in color, soft and gelatinous, but not clearly delineated. Microscopically, the mass consisted of diffuse proliferated neoplastic oligodendroglial cells characterized by small, round, and hyperchromatic nuclei with clear cytoplasm and the cells aggressively invaded into the adjacent parenchyma. Immunohistochemistry demonstrated that most of the neoplastic cells were positive for S-100 protein, vimentin, neuron specific enolase (NSE), and neurofilament protein (NFP). From these findings, the mass was diagnosed as oligodendroglioma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14610376/