Peer-reviewed veterinary case report
Oligodendroglioma with Neuronal Differentiation in Two Boxer Dogs.
- Journal:
- Journal of comparative pathology
- Year:
- 2019
- Authors:
- Cornax, I et al.
- Affiliation:
- Medical School · United States
- Species:
- dog
Abstract
Two cases of high-grade glioma comprising sheets of oligodendroglial cells multifocally disrupted by regions of remarkable neuronal differentiation are described. These tumours morphologically resemble 'oligodendroglioma with ganglioglioma-like maturation', a rare tumour of man, but appear to be phenotypically more aggressive. Neuronal markers (synaptophysin, neuron-specific enolase and βIII-tubulin) effectively highlight neuronal elements within these tumours and could potentially help to further investigate the prevalence and biological significance of neuronal differentiation in canine oligodendroglioma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31690408/