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Peer-reviewed veterinary case report

Fish oil reduces heart rhythm problems in Boxer dogs with ARVC

By Smith, Caren E et al.·Published in Journal of veterinary internal medicine·2007·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Omega-3 fatty acids in Boxer dogs with arrhythmogenic right ventricular cardiomyopathy.

Species:
dog

Plain-English summary

A group of 24 Boxer dogs with a heart condition called arrhythmogenic right ventricular cardiomyopathy (ARVC) were studied to see if fish oil could help reduce their irregular heartbeats. The dogs were given either fish oil, flax oil, or sunflower oil for six weeks. The results showed that the dogs receiving fish oil had a significant decrease in the number of irregular heartbeats compared to those on the other oils. This suggests that fish oil could be a helpful treatment for Boxers with this heart issue, but more research is needed to find the best dosage and treatment duration.

People also search for: Boxer dog heart problems · fish oil for dog arrhythmia · treating Boxer arrhythmogenic right ventricular cardiomyopathy

Abstract

BACKGROUND: Omega-3 fatty acids have been shown to reduce arrhythmia in animal models and people. These effects have not been studied in dogs with spontaneously occurring arrhythmia. HYPOTHESIS: Fish oil will reduce the frequency of ventricular arrhythmia in Boxer dogs with arrhythmogenic right ventricular cardiomyopathy (ARVC). ANIMALS: Twenty-four Boxers with ARVC were included in this study. METHODS: Asymptomatic Boxers not receiving antiarrhythmic medications were evaluated with echocardiogram and electrocardiogram. Dogs with at least 1 ventricular premature contraction (VPC) received 24-hour ambulatory electrocardiography (AECG) recordings. Dogs with > 95 VPCs in 24 hours were randomized to 1 of 3 treatments: (1) Fish oil, 2 g; (2) Flax oil, 2 g; or (3) sunflower oil, 2 g (Control group), for 6 weeks. Investigators and owners were blinded to the treatment groups. All baseline measurements were repeated after the 6-week supplementation. RESULTS: There were no differences at baseline for age, sex, blood pressure, weight, echocardiographic measurements, or VPCs. Median number of VPCs in 24 hours for all dogs was 543 (range, 96-40,063) at baseline and 193 (range, 6-14,825) after 6 weeks of supplementation. VPCs/24 h were reduced for the Fish oil group (baseline median = 397 [range, 249-10,587]; 6-week median = 162 [range, 16-3,781]; P = .02), but not for the Flax oil (P = .58) or Control (P = .48) groups. CONCLUSIONS AND CLINICAL IMPORTANCE: These data suggest that fish oil, but not flax oil, supplementation for 6 weeks reduces arrhythmia in Boxers with ARVC and that it could be useful in treating this common disease. Further studies are needed to determine optimal dose and duration of treatment.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17427387/