Peer-reviewed veterinary case report
One-stage anterior approach for four-vessel occlusion in rat.
- Journal:
- Stroke
- Year:
- 2005
- Authors:
- Yamaguchi, Mitsuo et al.
- Affiliation:
- Department of Neurosurgery · United States
- Species:
- rodent
Abstract
BACKGROUND AND PURPOSE: We report a modified 4-vessel occlusion (4VO) rat model. METHOD: We used a 1-stage anterior approach for making bilateral hemispheric ischemia. RESULTS: Modified 4VO method decreased cerebral blood flow to 12% to 14% of baseline levels. CONCLUSIONS: This modified 4VO method is a minimally invasive, quick, reliable procedure for producing ischemic changes.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16166575/