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Peer-reviewed veterinary case report

Onset of protection from experimental infection with type 2 bovine viral diarrhea virus following vaccination with a modified-live vaccine.

Journal:
Veterinary therapeutics : research in applied veterinary medicine
Year:
2007
Authors:
Brock, K V et al.
Affiliation:
Department of Pathobiology · United States

Abstract

The onset of protection after the administration of a modified-live bovine viral diarrhea virus (BVDV) vaccine was determined. Protection was determined following experimental infection with a virulent type-2 BVDV (strain 1373) in cattle vaccinated 3, 5, or 7 days before BVDV infection. Protection, as measured by reduced virus shedding, lack of leukopenia, reduction in viremia, and reduced mortality, was present as early as 3 days after vaccination with a single dose of modified-live BVDV vaccine. Complete protection was obtained in cattle vaccinated 5 or 7 days before BVDV experimental infection.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17447228/