Peer-reviewed veterinary case report
Retina and optic nerve scans in dogs with glaucoma
By Graham, Kathleen L et al.·Published in Veterinary ophthalmology·2020·Sydney Medical School, United Kingdom·View original on PubMed →
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Original publication title: Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma.
- Species:
- dog
Plain-English summary
A group of 24 dogs with glaucoma had their eyes examined using a special imaging technique called optical coherence tomography (OCT) to look at the retina and optic nerve. The study found that dogs with glaucoma had thinner retinas and nerve fiber layers compared to healthy dogs. This suggests that OCT could be a useful tool for veterinarians to assess eye health in dogs at risk for glaucoma. Further research is needed to confirm these findings and improve the reliability of the measurements.
People also search for: dog glaucoma symptoms · dog eye exam OCT · how to treat glaucoma in dogs
Abstract
OBJECTIVE: To evaluate the retina and optic nerve head (ONH) in canine eyes predisposed to glaucoma using optical coherence tomography (OCT). ANIMALS: Twenty-five eyes (24 dogs). METHODS: Measures of peripapillary retinal, retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) thickness and ONH parameters were obtained in vivo by OCT of the unaffected eye in dogs diagnosed with unilateral primary glaucoma (predisposed; n = 12) and compared with measures of healthy control eyes (normal; n = 13). Repeatability and intrarater reliability were explored using intraclass correlation coefficients (ICC). RESULTS: Compared to normal eyes, predisposed eyes had a thinner retina in the temporal (P = 0.005), inferior quadrants (P = 0.003), and decreased inner retinal thickness (superior: P = 0.003, temporal: P = 0.001, inferior: P < 0.001, nasal: P = 0.001). Predisposed eyes had a thinner RNFL compared to normal eyes (P = 0.005), and when analyzed in quadrants, it was thinner in the superior (P < 0.001), temporal (P = 0.034), and nasal quadrants (P = 0.001). Repeatability (ICC 0.763-0.835) and intrarater reliability (ICC 0.824-0.942) were good to excellent for measures of retinal thickness and adequate for RNFL measurements (ICC 0.701-0.798). Reliable measurements of optic disk area were obtained and were similar between groups (P = 0.597). Measurements of parameters relying on automated software detection (GCC, optic cup, optic rim) had inadequate repeatability and reliability. CONCLUSION: Statistically significant differences in retinal and RNFL thicknesses were identified in normal and predisposed eyes. Reliable and consistent measurements of variables with manual adjustment of software detected parameters were obtained. Validation of OCT as a diagnostic tool for clinical assessment in canine glaucoma is warranted.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31297979/