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Peer-reviewed veterinary case report

Optimizing bioluminescence imaging to study protozoan parasite infections.

Journal:
Trends in parasitology
Year:
2014
Authors:
Taylor, Martin C & Kelly, John M
Affiliation:
Department of Pathogen Molecular Biology · United Kingdom

Abstract

Bioluminescence imaging is a non-invasive technique which can be used to monitor infections in real-time. However, its utility is restricted by difficulties in detecting pathogens in deep tissue. 'Red-shifted' luciferases, which emit light of longer wavelength than standard bioluminescence-generating proteins, greatly enhance sensitivity, and have wide applicability for studying parasite infections.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24485045/