Peer-reviewed veterinary case report
Oral bleeding in dogs with pancreatic insufficiency from enzyme
By Rutz, Gabriele M et al.·Published in Journal of the American Veterinary Medical Association·2002·Department of Small Animal Medicine and Surgery, United States·View original on PubMed →
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Original publication title: Oral bleeding associated with pancreatic enzyme supplementation in three dogs with exocrine pancreatic insufficiency.
- Species:
- dog
Plain-English summary
Three dogs with exocrine pancreatic insufficiency (a condition where the pancreas doesn't produce enough enzymes for digestion) started bleeding from their mouths after taking pancreatic enzyme supplements with their meals. The bleeding stopped when their owners reduced the amount of the supplement given. In two of the dogs, this dose reduction did not cause any issues with their stool, but the third dog had a return of symptoms when the dose was lowered. This suggests that while high doses of these supplements can lead to oral bleeding, most dogs can manage the issue by simply taking a smaller dose.
People also search for: dog oral bleeding pancreatic enzyme · exocrine pancreatic insufficiency treatment · dog bleeding after meals
Abstract
Three dogs with exocrine pancreatic insufficiency developed oral bleeding during treatment with pancreatic enzyme supplements. According to the owners of the dogs, bleeding from the oral cavity developed during or shortly after consumption of meals containing the pancreatic enzyme supplement. Oral bleeding stopped in all dogs when owners reduced the dose of the pancreatic enzyme supplement. In 2 dogs, the decrease in the dose of the pancreatic enzyme supplement did not affect fecal consistency. However, in the third dog, the decrease in dose led to a recurrence of clinical signs. Findings in these dogs suggest that high doses of pancreatic enzyme supplements can cause oral bleeding in dogs with pancreatic insufficiency, but that oral bleeding can be successfully managed by dose reduction in most dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12494968/