Peer-reviewed veterinary case report
Oral eosinophilic granuloma causing ulcers in Cavalier King Charles
By Bredal, W P et al.·Published in The Journal of small animal practice·1996·Department of Small Animal Clinical Sciences·View original on PubMed →
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Original publication title: Oral eosinophilic granuloma in three cavalier King Charles spaniels.
- Species:
- dog
Plain-English summary
Three Cavalier King Charles Spaniels were brought in with painful oral ulcers, which made it hard for them to eat and swallow. They showed signs like throat clearing, coughing during meals, and a reduced appetite. The vets diagnosed them with a rare condition called oral eosinophilic granuloma, confirmed through tissue samples. Treatment with glucocorticoids (a type of steroid) had mixed results; some dogs improved significantly while others did not respond well. The exact cause of this condition remains unknown, but it may be related to an allergic reaction.
People also search for: Cavalier King Charles Spaniel oral ulcers · dog swallowing problems treatment · eosinophilic granuloma in dogs
Abstract
Oral eosinophilic granuloma is a rare and enigmatic disease in dogs. The clinical, haematological, cytological and histopathological features of three unrelated Cavalier King Charles spaniels with oral ulcers are presented. The disease was characterised by granuloma or plaque formation in the oral cavity. Common clinical signs were clearing the throat, swallowing problems, coughing during and after meals, reduced appetite and difficulty in eating. Haematological findings were not specific. Cytology was considered easier to perform than tissue biopsy due to friability of the tissue, but could not be used to confirm a granuloma diagnosis. The diagnosis of oral eosinophilic granuloma was verified histopathologically in each case. Response to glucocorticoid therapy varied, from complete remission to lack of any visible effect, leading to a guarded prognosis. The aetiology of the disease was not determined; however, the gross and microscopic morphologies of the lesions, their location and the response to corticosteroid therapy was suggestive of hypersensitivity.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8912245/