Peer-reviewed veterinary case report
Dog with C. difficile diarrhea treated by oral fecal transplant
By Koji Sugita et al.·Published in BMC Veterinary Research·2019·View original on Semantic Scholar →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Oral faecal microbiota transplantation for the treatment of Clostridium difficile-associated diarrhoea in a dog: a case report
- Species:
- dog
Plain-English summary
An 8-month-old male French bulldog was suffering from diarrhea for four months, which was linked to a Clostridium difficile infection. After tests confirmed the presence of this bacteria, the dog was treated with a fecal microbiota transplant (FMT), where healthy stool from another dog was given orally. Within just a few days, the dog's stool returned to normal, and follow-up tests showed no signs of the infection. This treatment was successful and had no side effects, suggesting that FMT could be a good option for similar gastrointestinal issues in dogs.
People also search for: dog diarrhea treatment · Clostridium difficile in dogs · fecal transplant for dogs · French bulldog diarrhea · dog gut health solutions
Abstract
BackgroundSuccessful clinical outcomes of faecal microbiota transplantation (FMT) for recurrent Clostridium difficile infection have been reported in humans and a marmoset. However, it has been unclear whether oral FMT was effective for the treatment of C. difficile-associated diarrhoea in dogs.Case presentationAn 8-month-old, intact male French bulldog was presented with a 4-month history of intermittent large bowel diarrhoea. Physical and clinical examinations did not identify any specific causes for diarrhoea. Real-time PCR analysis and immunochromatography detected C. difficile antigen and toxin A&B genes and proteins in a faecal sample. Based on these findings, diarrhoea in the dog was considered to be induced by C. difficile-associated colitis. The dog was treated with oral FMT, in which a faecal solution obtained from a healthy beagle was orally administered to the subject. Stool consistency and frequency and faecal blood and mucus became normal 2–3 days after oral FMT, and real-time PCR analysis and immunochromatography was negative for C. difficile antigen and toxin A&B genes and proteins. No adverse events were observed.ConclusionThe present case report demonstrated that oral FMT was an effective treatment for C. difficile-associated diarrhoea in a dog. The findings in this report provide a rationale to evaluate clinical efficacy of oral FMT for other gastrointestinal diseases in dogs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/30616615