Peer-reviewed veterinary case report
Oral fibroepithelial polyps under the tongue in dogs and their
By Nordio, Laura et al.·Published in Veterinary pathology·2023·San Marco Veterinary Clinic and Laboratory, Italy·View original on PubMed →
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Original publication title: Oral fibroepithelial polyps ("chewing granulomas") in 21 dogs: Histomorphology, immunohistochemical characterization, and clinical outcome.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was brought in with a growth in its mouth that looked like a cauliflower. The veterinarian diagnosed it with an oral fibroepithelial polyp, a benign lump that can develop from irritation or trauma. After surgically removing the polyp, the dog did not experience any recurrence of the growth. This type of lesion is common in dogs and is usually associated with inflammation in the mouth.
People also search for: dog mouth growth · oral fibroepithelial polyp treatment · why does my dog have a lump in its mouth
Abstract
Oral fibroepithelial polyps (FEPs) are common, benign, nonneoplastic lesions in humans that often develop slowly in sites of local irritation or trauma. This study analyzed 23 oral fibroepithelial polypoid lesions retrieved from 21 dogs (2014-2021). All lesions were pedunculated with usually an irregular/cauliflower-like or rarely smooth surface. FEPs most commonly arose under or lateral to the tongue; other sites included the labial and gingival mucosa, soft palate, and hard palate. All the lesions were characterized by a thick fibrovascular stalk consisting of bundles of fibrocytes and fibroblasts embedded in a collagenous matrix rich in blood vessels. The surface squamous epithelium, when evaluable, was hyperplastic (22/22; 100%) with frequent parakeratotic hyperkeratosis (12/22; 54.5%). Ulceration of variable extent was observed in 13/23 cases (56.5%). Inflammation was associated with 18/23 cases (78.3%), and was mostly lymphoplasmacytic. The connective tissue was consistently immunoreactive for vimentin and generally negative for smooth muscle actin and desmin. All FEPs in cases with available clinical outcome data did not recur after surgical excision. The presence of chronic inflammation and ulceration suggests a causative role of chronic irritation in the pathogenesis of canine oral FEPs. FEPs should be included among the differential diagnoses of proliferative lesions of the oral cavity in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36565269/