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Peer-reviewed veterinary case report

Oral side effects of dermatologic therapies: A systematic review and meta-analysis.

Year:
2025
Authors:
M Alqahtani R et al.
Affiliation:
Department of Dermatology

Abstract

Dermatologic treatments can produce clinically significant oral side effects that remain poorly quantified. A significant association between dermatologic therapies and oral complications (ES=1.55, 95% CI: 0.94-2.17, p<0.001) is observed, despite high heterogeneity (I<sup>2</sup>=96%). Retinoids were predominantly associated with cheilitis and xerostomia, immunosuppressants with mucositis and ulcerations, and JAK inhibitors with opportunistic infections. Thus, data shows the necessity of routine oral assessments and preventive strategies to reduce therapy-related morbidity.

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Original publication: https://europepmc.org/article/MED/41393498