Peer-reviewed veterinary case report
Oral ulceration and bleeding associated with pancreatic enzyme supplementation in a German shepherd with pancreatic acinar atrophy.
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2006
- Authors:
- Snead, Elisabeth
- Affiliation:
- Western College of Veterinary Medicine · Canada
- Species:
- dog
Plain-English summary
A 20-month-old German shepherd was diagnosed with a condition called pancreatic acinar atrophy, which means the pancreas isn't producing enough enzymes to help with digestion. To help, the dog was given pancreatic enzyme supplements, vitamin B12, and a medication called cimetidine. However, this treatment led to bleeding in the dog's mouth. After stopping the cimetidine, adjusting how the enzymes were mixed with the food, and providing treatment for the mouth sores, the dog's condition got better.
Abstract
A 20-month-old German shepherd with primary pancreatic acinar atrophy and exocrine pancreatic insufficiency that was treated with pancreatic enzyme supplementation, vitamin B12, and cimetidine developed oral bleeding. Following discontinuation of the cimetidine, increased preincubation of the enzymes with the food, and symptomatic therapy for the ulceration, the dog's condition improved.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16808232/