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Peer-reviewed veterinary case report

Orbital (retrobulbar) meningioma in a Simmental cow.

Journal:
Veterinary pathology
Year:
2007
Authors:
Reis, J L et al.
Affiliation:
Faculdade de Agronomia e Medicina Veterin&#xe1 · Brazil

Abstract

A 12-year-old Simmental cow was presented with a moderately firm irregular whitish mass of approximately 5 cm in diameter, occupying the right orbit. Microscopically, a poorly differentiated neoplasm was observed. The immunohistochemical panel included cytokeratins, vimentin, epithelial membrane antigen, Factor VIII, CD34, Mart-1, Melan A, smooth muscle actin, desmin, chromogranin, neuron-specific enolase, S-100 protein, and MIB-1. The neoplasm was negative for all of them, with the exception of vimentin and S-100 protein. Transmission electron microscopy revealed abundant desmosomes. These findings support the diagnosis of orbital (retrobulbar) meningioma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17606511/