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Peer-reviewed veterinary case report

Osborn waves on ECG linked to high calcium in a dog

By Murphy, L A et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2026·Friendship Hospital for Animals, United States·View original on PubMed

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Original publication title: Osborn waves secondary to hypercalcemia in a dog.

Species:
dog

Plain-English summary

A 7-year-old female spayed Vizsla was brought to the vet after eating a toxic amount of a vitamin D analogue, leading to symptoms like vomiting, excessive drooling, and increased thirst. Blood tests showed she had dangerously high calcium levels. To manage this, the dog was hospitalized and treated for hypercalcemia (high calcium in the blood). An electrocardiogram (ECG) revealed unusual heart wave patterns known as Osborn waves, which have been seen in humans but are reported here for the first time in a dog. With proper treatment, the dog was stabilized and her condition improved.

People also search for: dog vomiting and drooling · Vizsla high calcium treatment · vitamin D toxicity in dogs

Abstract

A seven-year-old female spayed Vizsla was presented on referral for evaluation after ingesting a toxic dose of a vitamin D analogue (calciportriol). The owners had noted vomiting, ptyalism, and polydipsia prior to evaluation. Blood work was performed, which confirmed a severe ionized hypercalcemia, and the dog was admitted for medical management of the hypercalcemia. An electrocardiogram was performed due to the severity of the hypercalcemia, which revealed Osborn waves. While Osborn waves have been reported in cases of hypercalcemia in humans, this is the first case of Osborn waves in a dog associated with severe hypercalcemia.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41478242/