Peer-reviewed veterinary case report
Survival times in dogs with invasive adrenal tumors without surgery
By Fontes, Gabrielle S et al.·Published in Journal of the American Veterinary Medical Association·2024·View original on PubMed →
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Original publication title: Outcome in dogs with invasive adrenal gland tumors that did not pursue adrenalectomy.
- Species:
- dog
Plain-English summary
A group of 32 dogs with invasive adrenal tumors (growths on the adrenal glands) that did not have surgery were studied to see how long they survived. Most of these dogs had tumors that invaded nearby blood vessels, and many owners chose not to pursue surgery due to the high risks involved. Out of the group, only 2 dogs survived beyond the initial follow-up period, with a median survival time of just 50 days. The majority of the dogs either died or were euthanized, often due to internal bleeding.
People also search for: dog adrenal tumor treatment · invasive adrenal tumor in dogs · dog cancer survival rates · dog hemoabdomen symptoms · non-surgical treatment for dog tumors
Abstract
OBJECTIVE: To report the survival times in dogs diagnosed with adrenal tumors with vascular or soft tissue invasion that did not undergo adrenalectomy. ANIMALS: Retrospective case series of 32 client-owned dogs. METHODS: The medical records of a referral veterinary hospital were reviewed to identify dogs that were diagnosed with an invasive adrenal mass and did not undergo adrenalectomy between January 2013 and December 2022. Data collected included signalment, examination findings, and diagnostic results from the initial presentation. Descriptive statistics were calculated to summarize dog signalment information, and Kaplan-Meier survival analysis was performed for calculation of median survival time. RESULTS: Most dogs (n = 28) had vascular invasion, primarily into the caudal vena cava. Surgery was offered but not pursued due to perceived risk of sudden death (n = 5), risk of hemorrhage (4), or concurrent diagnosis of disseminated intravascular coagulation (1). Only 1 dog pursued stereotactic body radiation therapy, and 1 was prescribed toceranib phosphate (Palladia). Of these 32 dogs, 30 (93.8%) died or were euthanized and 2 (6.2%) dogs survived. The median follow-up time was 49 days (range, 0 to 1,910 days). The median survival time was 50 days (95% CI, 4 to 194 days). The most common cause of death or euthanasia was hemoabdomen (n = 8). CLINICAL RELEVANCE: Nonsurgical management of invasive adrenal tumors was associated with short survival times in this case series.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38599229/